Neil Klinger MD

Neil Klinger MD

Neurosurgery, Year 2

Neil Klinger MD

Narrative Bio

Neil Klinger grew up in northern Michigan. He attended Grand Valley State University for his bachelor's degree. He then pursued a master’s degree researching the protein chemistry of enzymes involved in bacterial antibiotic resistance. While attending Wayne State University School of Medicine, his interest in research led him to work on neuro-oncology projects in Dr. Sandeep Mittal’s lab. In his spare time, Neil enjoys spending time with his family and cooking.


Wayne State University/Detroit Medical Center
Detroit, Michigan


Guastella AR, Michelhaugh SK, Klinger NV, Fadel HA, Kiousis S, Ali-Femhi R, Kupsky WJ, Juhász C, Mittal S: Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors. J Neurooncol: In Press, 2018

Fadel H, Klinger NV, Beer P, Tariq F, Smith C, Seman S, Hugeller J, Zwillman M, Moisi M, Johnson R. Aortic Stenting and Thoracolumbar Fusion after Traumatic ASIA A Thoracic Dislocation. The Spine Scholar: 2017

Sundaram SK, Michelhaugh SK, Klinger NV, Kupsky WJ, Sood S, Chugani HT, Mittal S, Juhász C: GNAQ Mutation in the Venous Vascular Malformation and Underlying Brain Tissue in Sturge-Weber Syndrome. Neuropediatrics: 48:385-389, 2017

Mittal S, Klinger NV, Michelhaugh SK, Barger GR, Pannullo SC, Juhasz C: Alternating electric tumor treating fields for treatment of glioblastoma: rationale, preclinical, and clinical studies. J Neurosurg:1-8, 2017

Bosnyak E, Michelhaugh SK, Klinger NV, Kamson DO, Barger GR, Mittal S, et al: Prognostic Molecular and Imaging Biomarkers in Primary Glioblastoma. Clin Nucl Med 42:341-347, 2017

Michelhaugh SK, Muzik O, Guastella AR, Klinger NV, Polin LA, Cai H, et al: Assessment of Tryptophan Uptake and Kinetics Using 1-(2-18F-Fluoroethyl)-l-Tryptophan and alpha-11C-Methyl-l-Tryptophan PET Imaging in Mice Implanted with Patient-Derived Brain Tumor Xenografts. J Nucl Med 58:208-213, 2017

Klinger NV, Shah AK, Mittal S: Management of brain tumor-related epilepsy. Neurol India 65:S60-s70, 2017

Guastella AR, Michelhaugh SK, Klinger NV, Kupsky WJ, Polin LA, Muzik O, et al: Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma. Mol Imaging 15, 2016

Klinger NV, Mittal S: Therapeutic Potential of Curcumin for the Treatment of Brain Tumors. Oxid Med Cell Longev 2016:9324085, 2016

Klinger NV, Mittal S: Clinical efficacy of deep brain stimulation for the treatment of medically refractory epilepsy. Clin Neurol Neurosurg 140:11-25, 2016

Michelhaugh SK, Guastella AR, Varadarajan K, Klinger NV, Parajuli P, Ahmad A, et al: Development of patient-derived xenograft models from a spontaneously immortal low-grade meningioma cell line, KCI-MENG1. J Transl Med 13:227, 2015

Mitchell JM, Clasman JR, June CM, Kaitany KC, LaFleur JR, Taracila MA, Klinger NV, et al: Structural basis of activity against aztreonam and extended spectrum cephalosporins for two carbapenem-hydrolyzing class D beta-lactamases from Acinetobacter baumannii. Biochemistry 54:1976-1987, 2015

Kaitany KC, Klinger NV, June CM, Ramey ME, Bonomo RA, Powers RA, et al: Structures of the class D Carbapenemases OXA-23 and OXA-146: mechanistic basis of activity against carbapenems, extended-spectrum cephalosporins, and aztreonam. Antimicrob Agents Chemother 57:4848-4855, 2013